This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial. Lancet 2018; 391: 51–58.
Published: 22nd February 2018
Authors: Van Brunschot S, van Grinsven J, van Santvoort HC, Bakker OJ, Besselink MG, Boermeester MA et al.
Conclusion
Ninety-eight patients were randomly assigned to endoscopic drainage followed by endoscopic necrosectomy if indicated, or percutaneous drainage followed by video-assisted retroperitoneal debridement. Rates of death or major complication within six months were similar: 43 versus 45 per cent, respectively; P=0.5. Mortality rates were similar.
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