This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Endoscopic transgastric vs. surgical necrosectomy for infected necrotizing pancreatitis. A randomized trial. JAMA 2012; 307: 1053–1061.

Published: 27th August 2012

Authors: Bakker OJ, van Santvoort HC, van Brunschot S, Geskus RB, Besselink MG, Bollen TL et al. et al.

Conclusion

The endpoint in this study with 20 patients for analysis was the post procedure inflammatory response, which was reduced in patients who had the endoscopic procedure (P=0.004). Death and major complication rates were also reduced, as was the number of pancreatic fistulas: 10 versus 70 per cent, P=0.02.

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