This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Evaluation of cell therapy on exercise performance and limb perfusion in peripheral artery disease. Circulation. 2017; 135: 1417-1428.

Published: 28th November 2017

Authors: Perin EC, Murphy MP, March KL, Bolli R, Loughran J, Yang PC et al.

Conclusion

Eighty-two patients with claudication were randomized to ten injections of active cells into the thigh and calf, or placebo. There were no functional improvements in limb perfusion after six months in either group, or changes in quality of life. Nor were there any harms.

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