This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Extended antibiotic therapy versus placebo after laparoscopic cholecystectomy for mild and moderate acute calculous cholecystitis: A randomized double-blind clinical trial. Surgery 2018; 164: 24-30.

Published: 22nd November 2018

Authors: de Santibañes M, Glinka J, Pelegrini P, Alvarez FA, Elizondo C, Giunta D et al.

Conclusion

An additional five days of antibiotics did not reduce the rate of infective complications (5.8 per cent versus 6.6 per cent with placebo) in this trial that included 195 procedures.

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