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Extended versus conventional thromboprophylaxis after major abdominal and pelvic surgery: Systematic review and meta-analysis of randomized clinical trials. Surgery 2018; 164: 1234-1240.

Published: 29th April 2019

Authors: Rausa E, Kelly ME, Asti E, Aiolfi A, Bonitta G, Winter DC et al.


Four RCTs were included. Extended prophylaxis reduced the risk of venous thromboembolism (VTE) without increasing the rate of bleeding; number needed to treat to prevent one VTE was 14.

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