The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Five-year follow-up of antibiotic therapy for uncomplicated acute appendicitis in the APPAC randomized clinical trial. JAMA 2018; 320: 1259-1265.

Published: 19th December 2018

Authors: Salminen P, Hannu Paajanen T, Rautio T, Nordström P, Aarnio M, Rantanen T et al.

Conclusion

After 5 years, the cumulative risk of recurrent appendicitis was 39.1 per cent. Some 85/257 patients initially treated with antibiotics had undergone appendicectomy; all but seven had confirmed appendicitis.

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