The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial. J Clin Oncol 2011; 29: 4105–4112.

Published: 30th April 2012

Authors: Loehrer Sr PJ, Feng Y, Cardenes H, Wagner L, Brell JM, Cella D et al.

Conclusion

The addition of radiotherapy to chemotherapy was studied in 74 patients with an inoperable tumour. The radiotherapy group had prolonged survival (11.1 versus 9.2 months, P=0.017), but at the expense of more toxicity.

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