The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Immediate oral refeeding in patients with mild and moderate acute pancreatitis. A multicenter, randomized controlled trial (PADI trial). Ann Surg 2021; 274: 255-263.

Published: 9th December 2021

Authors: Ramírez-Maldonado E, Gordo SL, Pueyo EM, Sánchez-García A, Mayol S, González S et al.


Some 131 patients were included in the study. Immediate oral feeding reduced mean duration of hospital stay from 8.8 to 3.4 days (P<0.001), and reduced the rate of complications (8 versus 26 per cent), and costs.

Pubmed Link