This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Impact of perioperative administration of synbiotics in patients with esophageal cancer undergoing esophagectomy: a prospective randomized controlled trial. Surgery 2012; 152: 832–842.

Published: 4th March 2013

Authors: Tanaka K, Yano M, Motoori M, Kishi K, Miyashiro I, Ohue M et al. et al.

Conclusion

Synbiotics appeared to reduce the duration of the systemic inflammatory response associated with surgery (P=0.006). The results was fewer postoperative infections: 10 versus 29 per cent, P=0.068.

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