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Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass. A systematic review and meta-analysis of weight loss, comorbidities, and biochemical outcomes from randomized controlled trials. Ann Surg 2021; 273: 66-74.

Published: 7th April 2021

Authors: Lee Y, Doumouras A, Yu J, Aditya I, Gmora S, Anvari M et al.


Some 33 RCTs involving 2457 patients were analyzed. Roux-en-Y bypass resulted in greater loss of body mass (mean difference 1.25Kg, P=0.001), which persisted to three years. It also was more likely to resolve dyslipidaemia after one year (P<0.001), but effects on diabetes and hypertension were similar.

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