This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass. A systematic review and meta-analysis of weight loss, comorbidities, and biochemical outcomes from randomized controlled trials. Ann Surg 2021; 273: 66-74.

Published: 7th April 2021

Authors: Lee Y, Doumouras A, Yu J, Aditya I, Gmora S, Anvari M et al.

Conclusion

Some 33 RCTs involving 2457 patients were analyzed. Roux-en-Y bypass resulted in greater loss of body mass (mean difference 1.25Kg, P=0.001), which persisted to three years. It also was more likely to resolve dyslipidaemia after one year (P<0.001), but effects on diabetes and hypertension were similar.

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