This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Local treatment of unresectable colorectal liver metastases: results of a randomized phase II trial. J Natl Cancer Inst 2017; 109. doi: 10.1093/jnci/djx015.
Published: 5th January 2018
Authors: Ruers T, Van Coevorden F, Punt CJA, Pierie J-PEN, Borel-Rinkes I, Ledermann JA et al.
Conclusion
Some 119 patients with irresectable liver metastasis were offered chemotherapy with, or without radio frequency ablation. After a median of 9.7 years, patients who had radiofrequency had improved overall survival: hazard ratio 0.58, 95 per cent confidence interval 0.38 to 0.88, P=0.01.
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