This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Low-dose aspirin for primary prevention of cardiovascular events in patients with type 2 diabetes mellitus. 10-year follow-up of a randomized controlled trial. Circulation. 2017; 135: 659-670.

Published: 2nd August 2017

Authors: Saito Y, Okada S, Ogawa H, Soejima H, Sakuma M, Nakayama M et al.

Conclusion

Some 2539 diabetic patients without previous vascular disease were followed for a median of 10.3 years. Aspirin did not reduce the risk of cardiovascular complications (hazard ratio 1.04, 95 per cent confidence interval 0.83 to 1.3), but did increase the risk of gastrointestinal bleeding (2 versus 0.9 per cent, P=0.03).

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