This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Low ligation of inferior mesenteric artery in laparoscopic anterior resection for rectal cancer reduces genitourinary dysfunction. Results from a randomized controlled trial (HIGHLOW Trial). Ann Surg 2019; 269: 1018-1024.

Published: 2nd September 2019

Authors: Mari G, Crippa J, Cocozza E, Berselli M, Livraghi L, Carzaniga P et al.

Conclusion

There were no differences in perioperative outcomes and initial oncological outcomes in this study that included 214 patients. Patients who had low mesenteric ligation had improved quality of life after 9 months, better continence and fewer obstructive urological symptoms.

You may also be interested in

Scientific Surgery

Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): 10-year follow-up of an open-label, non-inferiority, randomised controlled trial. Lancet Gastro Hepatol 2021; 6: 569-577.

Authors: Park JW, Kang S-B, Hao J, Lim S-B, Choi HS, Kim D-W et al.

Scientific Surgery

Perioperative systemic therapy vs cytoreductive surgery and hyperthermic intraperitoneal chemotherapy alone for resectable colorectal peritoneal metastases. A phase 2 randomized clinical trial. JAMA Surg 2021; 156: 710-720.

Authors: Rovers KP, Bakkers C, Nienhuijs SW, Burger JWA, Creemers G-JM, Thijs AMJ et al.

Scientific Surgery

Colonic J-pouch or straight colorectal reconstruction after low anterior resection for rectal cancer: impact on quality of life and bowel function: a multicenter prospective randomized study. Dis Colon Rectum 2020; 63: 1511-1523.

Authors: Gavaruzzi T, Pace U, Giandomenico F, Pucciarelli S, Bianco F, Selvaggi F et al.

Scientific Surgery

Meta-analysis and trial sequential analysis of randomized controlled trials comparing high and low ligation of the inferior mesenteric artery in rectal cancer surgery. Dis Colon Rectum 2020; 63: 988-999.

Authors: Hajibandeh S, Hajibandeh S, Maw A

Scientific Surgery

Two-stage Turnbull-Cutait pull-through coloanal anastomosis for low rectal cancer. A randomized clinical trial. JAMA Surg 2020; 155: e201625.

Authors: Biondo S, Trenti L, Espin E, Bianco F, Barrios O, Falato A et al.

Scientific Surgery

Organ preservation with chemoradiotherapy plus local excision for rectal cancer: 5-year results of the GRECCAR 2 randomised trial. Lancet Gastroenterol Hepatol 2020; 5: 465-474.

Authors: Rullier E, Vendrely V, Rouanet P, Tuech JJ, Valverde A

Scientific Surgery

Laparoscopic versus open resection for rectal cancer. A non-inferiority meta-analysis of quality of surgical resection outcomes. Ann Surg 2019; 269: 849-855.

Authors: Acuna SA, Chesney TR, Ramjist JK, Shah PS, Kennedy ED, Naxter NN et al.

Scientific Surgery

Clinical outcome after rectal replacement with side-to-end, colon-J-pouch, or straight colorectal anastomosis following total mesorectal excision. A Swiss Prospective, Randomized, Multicenter Trial (SAKK 40/04). Ann Surg 2019; 269: 827-835.

Authors: Marti W, Curti G, Wehrli H, Grieder F, Graf M, Gloor B et al.

Scientific Surgery

Better function with a colonic J-pouch or a side-to-end anastomosis? A randomized controlled trial to compare the complications, functional outcome, and quality of life in patients with low rectal cancer after a J-pouch or a side-to-end anastomosis. Ann Surg 2019; 269: 815-826.

Authors: Parc Y, Ruppert R, Fuerst A, Golcher H, Zutshi M, Hull T et al.

Scientific Surgery

A meta-analysis of randomized controlled trials on the use of suction drains following rectal surgery. Dig Surg 2018; 35: 482–490.

Authors: Guerra F, Giuliani G, Coletta D, Boni M, Rondelli F, Bianchi PP et al.

Scientific Surgery

Robotic versus laparoscopic minimally invasive surgery for rectal cancer: a systematic review and meta-analysis of randomized controlled trials. Ann Surg 2018; 267: 1034-1046.

Authors: Prete FP, Pezzolla A, Prete F, Testini M, Marzaioli R, Patriti A et al.

Scientific Surgery

Tattooing improves the detection of small lymph nodes and increases the number of retrieved lymph nodes in patients with rectal cancer who receive preoperative chemoradiotherapy: a randomized controlled clinical trial. Am J Surg 2018; 215: 563-569.

Authors: Okada K, Sahahiro S, Ogimi T, Miyakita H, Saito G, Tanaka A et al.