This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Menopausal hormone therapy after breast cancer: the Stockholm randomized trial. J Natl Cancer Inst 2005; 97: 533-555.

Published: 1st January 2005

Authors: von Schoultz E, Rutqvist LE on behalf of the Stockholm Breast Cancer Study Group.

Conclusion

Late results from two trials that included over 800 women were reviewed. In the first trial the risk of breast cancer was significantly increased with HRT use after follow-up of only 2.1 years (relative hazard 3.3, 95 per cent confidence interval 1.5 to 7.4), but after median of 4.1 years in the Stockholm trial the risk was not affected (0.82, 0.35 to 1.9).

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