The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Meta-analysis and trial sequential analysis of prophylactic negative pressure therapy for groin wounds in vascular surgery. J Vasc Surg 2019; 70: 1700–1710

Published: 23rd December 2019

Authors: Antoniou GA, Onwuka CC, Antoniou SA, Russell D


The analysis included 733 groin wounds in six RCTs. Negative pressure wound therapy reduced the rate of surgical site infection (odds ratio 0.36, 95 per cent confidence interval 0.24 to 0.54, P<0.001), and was associated with less redo surgery (0.44, 0.22 to 0.88, P=0.02) and shorter hospital stay (P=0.01).

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