This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Methylene blue intra-arterial staining of resected colorectal cancer specimens improves accuracy of nodal staging: A randomized controlled trial. Eur J Surg Oncol 2016; 42: 1642–1646.

Published: 30th March 2017

Authors: Reima H, Saar H, Innos K, Soplepmann J

Conclusion

The study included 266 colorectal cancer specimens. Methylene blue injection into the specimen after removal increased the median number of lymph nodes harvested for pathology to 27 compared with 16 in the no dye group, P<0.001. The proportion with metastatic nodes was similar: 42 versus 43 per cent.

Pubmed Link

You may also be interested in

Scientific Surgery

Feasibility and safety of laparoscopic complete mesocolic excision (CME) for right-sided colon cancer. Short-term Outcomes. A Randomized Clinical Study. Ann Surg 2021; 274: 57-62.

Authors: Di Buono G , Buscemi S, Cocorullo G, Sorce V, Amato G, Bonventre G et al.

Scientific Surgery

Long-term outcomes of a randomized controlled trial of single-incision versus multi-port laparoscopic colectomy for colon cancer. Ann Surg 2021; 273: 1060-1065.

Authors: Watanabe J, Ishibe A, Suwa H, Ota M, Fujii S, Kubota K et al.

Scientific Surgery

Preoperative oral antibiotics and surgical-site infections in colon surgery (ORALEV): a multicentre, single-blind, pragmatic, randomised controlled trial. Lancet Gastroenterol Hepatol 2020; 5: 729-738.

Authors: Basany EE, Solis-Pena A, Pellino G, Kreisler E, Fraccalvieri D, Muinelo-Lorenzo M et al.

Scientific Surgery

Short-term outcomes of single-port versus multiport laparoscopic surgery for colon cancer. The SIMPLE multicenter randomized clinical trial. Ann Surg 2021; 273: 217-223.

Authors: Lee YS, Kim JH, Kim HJ, Lee SC, Kang BM, Kim CW et al.

Scientific Surgery

Prospective, randomized study on the use of prosthetic mesh to prevent a parastomal hernia in a permanent colostomy: results of a long-term follow-up. Dis Colon Rectum 2020; 63: 678-684.

Authors: Mäkäräinen-Uhlbäck EJ, Klintrup KHB, Vierimaa MT, Carpelan-Holmström MA, Kössi JAO, Kairaluoma MV et al.

Scientific Surgery

Long-term oncologic results after stenting as a bridge to surgery versus emergency surgery for malignant left-sided colonic obstruction. A multicenter randomized controlled trial (ESCO Trial). Ann Surg 2020; 272: 703-708.

Authors: Arezzo A, Forcignanò E, Bonino MA, Balagué C, Targarona E, Borghi F et al.

Scientific Surgery

Prophylactic intra-abdominal drainage following colorectal anastomoses. A systematic review and meta-analysis of randomized controlled trials. Am J Surg 2020; 219: 164-174.

Authors: Podda M, Di Saverio S, Davies JR, Atzeni J, Balestra F, Virdis F et al.

Scientific Surgery

Simple versus complex preoperative carbohydrate drink to preserve perioperative insulin sensitivity in laparoscopic colectomy. A randomized controlled trial. Ann Surg 2020; 271: 819-826

Authors: Karimian N, Kaneva P, Donatelli F, Stein B, Liberman AS, Charlebois P et al.

Scientific Surgery

Early versus standard closure of temporary ileostomy in patients with rectal cancer: a randomized controlled trial. J Surg Oncol 2019; 120: 249-299

Authors: Kuliavas J, Dulskas A, Kryzauskas M, Pauza K, Kilius A, Rudinskaite G et al.

Scientific Surgery

Intracorporeal or extracorporeal ileocolic anastomosis after laparoscopic right colectomy. A double-blinded randomized controlled trial. Ann Surg 2019; 270: 762-767.

Authors: Allaix M, Degiuli M, Bonino MA, Arezzo A, Mistrangelo M, Passera R et al.

Scientific Surgery

Disease-free survival and local recurrence after laparoscopic-assisted resection or open resection for rectal cancer. The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial. Ann Surg 2019; 269: 596-602.

Authors: Stevenson ARL, Solomon M, Brown CSB, Lumley JW, Hewett P, Clouston A et al.

Scientific Surgery

Disease-free survival and local recurrence for laparoscopic resection compared with open resection of stage II to III rectal cancer. Follow-up results of the ACOSOG Z6051 randomized controlled trial. Ann Surg 2019; 269: 589-595.

Authors: Fleshman J, Branda ME, Sargent DJ, Boller AM, George VV, Abbas MA et al.