The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial. Lancet 2017; 389: 1218–1228.

Published: 26th April 2017

Authors: Paramsothy S, Kamm MA, Kaakoush NO, Walsh AJ, van den Bogaerde J, Samuel D et al.

Conclusion

Eighty-five patients with active colitis were treated with enemas five days a week for eight weeks. Steroid-free remission occurred in 27 per cent of patients treated actively compared to 8 per cent given placebo, P=0.021. Adverse events were similar.

Pubmed Link