The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): 10-year follow-up of an open-label, non-inferiority, randomised controlled trial. Lancet Gastro Hepatol 2021; 6: 569-577.

Published: 9th December 2021

Authors: Park JW, Kang S-B, Hao J, Lim S-B, Choi HS, Kim D-W et al.


Median follow-up in this trial that enrolled 340 patients was 143 months. Overall 10-year survival rates were similar: 74.1 per cent open and 76.8 per cent laparoscopic surgery (P=0.44). Local recurrence rates were lower after laparoscopic surgery (3.4 versus 8.9 per cent; P=0.05), but disease-free survival rates were similar.

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