This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Optimal duration of extended adjuvant endocrine therapy for early breast cancer; results of the IDEAL Trial (BOOG 2006-05). J Natl Cancer Inst 2018; 110: 40-48.
Published: 9th August 2018
Authors: Blok EJ, Kroep JR, Kranenbarg EM-K, Duijm-de Carpentier M, Putter H, van den Bosch J et al.
Conclusion
There was no advantage to the longer course of letrozole in the study of 1824 women. Five year disease-free survival (hazard ratio 0.92, 95 per cent confidence interval 0.74 to 1.16) and overall survival rates (1.04, 0.78 to 1.38) were similar.
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