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Organ preservation with chemoradiotherapy plus local excision for rectal cancer: 5-year results of the GRECCAR 2 randomised trial. Lancet Gastroenterol Hepatol 2020; 5: 465-474.

Published: 15th October 2020

Authors: Rullier E, Vendrely V, Rouanet P, Tuech JJ, Valverde A


The 5-year results of this trial compared local excision with total mesorectal excision of low rectal cancer after downstaging by chemoradiotherapy (n=148 patients). Local recurrence rates were similar (both 7 per cent), as was survival: 84 per cent local excision versus 82 per cent total excision, P=0.88.

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