This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Organ preservation with chemoradiotherapy plus local excision for rectal cancer: 5-year results of the GRECCAR 2 randomised trial. Lancet Gastroenterol Hepatol 2020; 5: 465-474.

Published: 15th October 2020

Authors: Rullier E, Vendrely V, Rouanet P, Tuech JJ, Valverde A

Conclusion

The 5-year results of this trial compared local excision with total mesorectal excision of low rectal cancer after downstaging by chemoradiotherapy (n=148 patients). Local recurrence rates were similar (both 7 per cent), as was survival: 84 per cent local excision versus 82 per cent total excision, P=0.88.

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Laparoscopic versus open resection for rectal cancer. A non-inferiority meta-analysis of quality of surgical resection outcomes. Ann Surg 2019; 269: 849-855.

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Better function with a colonic J-pouch or a side-to-end anastomosis? A randomized controlled trial to compare the complications, functional outcome, and quality of life in patients with low rectal cancer after a J-pouch or a side-to-end anastomosis. Ann Surg 2019; 269: 815-826.

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Tattooing improves the detection of small lymph nodes and increases the number of retrieved lymph nodes in patients with rectal cancer who receive preoperative chemoradiotherapy: a randomized controlled clinical trial. Am J Surg 2018; 215: 563-569.

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