The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Oxygenated end-hypothermic machine perfusion in expanded criteria donor kidney transplant. A randomized clinical trial. JAMA Surg 2021; 156: 517-525.

Published: 24th November 2021

Authors: Husen P, Boffa C, Jochmans I, Krikke C, Davies L, Mazilescu L et al.


Some 305 kidneys awaiting transplant in cold storage were allocated to 2h machine perfusion or control groups. There was no difference in one year graft survival (92.1 per cent vs 93.3 per cent in controls, P=0.71), but the study was underpowered due to the high overall graft survival rate.

Pubmed Link