This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Povidone-iodine irrigation for pediatric perforated appendicitis may be protective. A Bayesian pilot randomized controlled trial. Ann Surg 2020; 271: 827-833

Published: 15th June 2020

Authors: Anderson KT, Putnam LR, Bartz-Kurycki MA, Hamilton EC, Yafi M, Pedroza C et al.

Conclusion

This pilot trial included 100 children. Use of iodine lavage reduced the risk of intra-abdominal abscess from 16 to 12 per cent (relative risk 0.72, 95 per cent credible interval 0.39 to 1.23). Bayesian analysis estimated an 89 per cent probability that iodine lavage is effective.

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