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Povidone-iodine irrigation for pediatric perforated appendicitis may be protective. A Bayesian pilot randomized controlled trial. Ann Surg 2020; 271: 827-833

Published: 15th June 2020

Authors: Anderson KT, Putnam LR, Bartz-Kurycki MA, Hamilton EC, Yafi M, Pedroza C et al.


This pilot trial included 100 children. Use of iodine lavage reduced the risk of intra-abdominal abscess from 16 to 12 per cent (relative risk 0.72, 95 per cent credible interval 0.39 to 1.23). Bayesian analysis estimated an 89 per cent probability that iodine lavage is effective.

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