This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Pre-surgical administration of microbial cell preparation in colorectal cancer patients: a randomized controlled trial. World J Surg 2016; 40: 1985–1992.

Published: 30th November 2016

Authors: Tan CK, Said S, Rajandram R, Wang Z, Roslani AC, Chin KF et al.

Conclusion

In this study that included 40 procedures, administration of the microbial cell preparation for seven days before surgery improved return of normal gut function (108.h versus 156.5h, P=0.022) and shortened hospital stay (median 6.5 versus 13 days, P=0.012).

You may also be interested in

Scientific Surgery

Heated fennel therapy promotes the recovery of gastrointestinal function in patients after complex abdominal surgery: A single-center prospective randomized controlled trial in China. Surgery 2020; 168: 793-799.

Authors: Chen B, He Y, Xiao Y, Guo D, Liu P, He Y et al.

Scientific Surgery

Transversus abdominis plane block in laparoscopic colorectal surgery: a systematic review. Dis Colon Rectum 2019; 62: 1248-1255

Authors: Wu RC, Jensen CC, Douaiher J, Madoff RD, Kwaan MR

Scientific Surgery

Comparison of bowel cleansing efficacy, safety, bowel movement kinetics, and patient tolerability of same-day and split-dose bowel preparation using 4 L of polyethylene glycol: a prospective randomized study. Dis Colon Rectum 2019; 62: 1518-1527

Authors: Seo M, Gweon T-G, Huh CW, Ji JS, Choi H

Scientific Surgery

Mechanical and oral antibiotic bowel preparation versus no bowel preparation for elective colectomy (MOBILE): a multicentre, randomised, parallel, single-blinded trial. Lancet 2019; 394: 840-848.

Authors: Koskenvuo L, Lehtonen T, Koskensalo S, Rasilainen S, Klintrup K, Ehrlich A et al.

Scientific Surgery

Administration of an oral hydration solution prevents electrolyte and fluid disturbances and reduces readmissions in patients with a diverting ileostomy after colorectal surgery: a prospective, randomized, controlled trial. Dis Colon Rectum 2018; 61: 840-846.

Authors: Migdanis A, Koukoulis G, Mamaloudis I, Baloyiannis I, Migdanis I, Kanaki M et al.

Scientific Surgery

Randomized controlled trial of two alcohol-based preparations for surgical site antisepsis in colorectal surgery. Ann Surg 2017; 266: 946-951.

Authors: Broach R, Paulson EC, Scott C, Mahmoud N

Scientific Surgery

Systematic review and meta-analysis of prophylactic mesh during primary stoma formation to prevent parastomal hernia. Dis Colon Rectum 2017; 60: 107-115.

Authors: Chapman SJ, Wood B, Drake TM, Young N, Jayne D

Scientific Surgery

Prophylactic mesh placement during formation of an end-colostomy reduces the rate of parastomal hernia: short-term results of the Dutch PREVENT-trial. Ann Surg 2017: 265: 663-669.

Authors: Brandsma H, Hansson B, Aufenacker TJ, van Geldere D, Lammeren FM, Mahabier C et al.

Scientific Surgery

Perioperative simvastatin therapy in major colorectal surgery: a prospective, double-blind randomized controlled trial. J Am Coll Surg 2016 223: 308–320.

Authors: Singh PP, Lemanu DP, Soop M, Bissett IP, Harrison J, Hill AG et al.

Scientific Surgery

Comparison of the risk of surgical site infection and feasibility of surgery between sennoside versus polyethylene glycol as a mechanical bowel preparation of elective colon cancer surgery: a randomized controlled trial. Surg Today 2016; 46: 735–740.

Authors: Tajima Y , Ishida H, Yamamoto A, Chika N, Onozawa H, Matsuzawa T et al.

Scientific Surgery

Comparing mechanical bowel preparation with both oral and systemic antibiotics versus mechanical bowel preparation and systemic antibiotics alone for the prevention of surgical site infection after elective colorectal surgery: a meta-analysis of randomized controlled clinical trials. Dis Colon Rectum 2016; 59: 70-78.

Authors: Chen M, Song X, Chen L, Lin Z-D, Zhang X-L

Scientific Surgery

Stapled versus handsewn intestinal anastomosis in emergency laparotomy: A systemic review and meta-analysis. Surgery 2015 157: 609-618.

Authors: Naumann DN, Bhangu A, Kelly M, Bowley DM