This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Preoperative intravenous iron to treat anaemia before major abdominal surgery (PREVENTT): a randomised, double-blind, controlled trial. Lancet 2020; 396: 1353-1361.

Published: 9th February 2021

Authors: Richards T, Baikady RR, Clevenger B, Butcher A, Abeysiri S, Chau M et al.

Conclusion

In this study that included 487 participants, intravenous iron given 10-42 days before surgery did not reduced the need for perioperative blood transfusion (105 in the iron group and 111 in controls), or the composite end point of death/transfusion: risk ratio 1.03, 95 per cent c.i. 0.78 to 1.37, P=0.84.

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