The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Prophylaxis of wound infections-antibiotics in renal donation (POWAR). A UK multicentre double blind placebo controlled randomised trial. Ann Surg 2020; 272: 65-71.

Published: 25th August 2020

Authors: Ahmed Z, Uwechue R, Chandak P, van Dellen D, Barwell J, Heap S et al.


The study was conducted among 273 donors who underwent hand-assisted laparoscopic nephrectomy for transplantation. Prophylactic antibiotics reduced the risk of postoperative infections: 23 versus 40.7 per cent (P=0.001), including surgical site infection 10.1 versus 20.7 per cent, P=0.012.

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