This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Quality of life after curative resection for rectal cancer in patients treated with adjuvant chemotherapy compared with observation: results of the randomized phase III SCRIPT Trial. Dis Colon Rectum 2019; 62: 711-720

Published: 24th January 2020

Authors: van der Valk MJ, Hilling DE, Meershoek-Klein Kranenbarg E, Peeters K, Kapiteijn E, Tsonaka R et al.

Conclusion

Results were available for 226 patients. The addition of chemotherapy resulted in a reduction in quality of life overall (P=0.006), and in physical functioning (P<0.001). All differences between the groups had resolved after twelve months.

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