Quality of life and patient satisfaction at 7-year follow-up of antibiotic therapy vs appendectomy for uncomplicated acute appendicitis. A secondary analysis of a randomized clinical trial. JAMA Surg 2020; 155: 283-289.

Published: 17th November 2020

Authors: Sippola S, Haijanen J, Viinikainen L, Gronroos J, Paajanen H, Rautio T et al.

Conclusion

Some 423 of the original 530 patients randomized were available for telephone follow-up. Of 206 initially given antibiotics, 39% later underwent appendicectomy. Quality-of-life was similar in both groups, but patients who had initial appendicectomy more likely to be satisfied with their treatment.

Pubmed Link

You may also be interested in

Scientific Surgery

Are postoperative intravenous antibiotics indicated after laparoscopic appendicectomy for simple appendicitis? A prospective double-blinded randomized controlled trial. Ann Surg 2020; 272: 248-252.

Authors: Mennie N, Panabokke G, Chang A, Tanny ST, Cheng W, Pacilli M et al.

Scientific Surgery

Non-operative treatment versus appendectomy for acute non-perforated appendicitis in children: five-year follow up of a randomized controlled pilot trial. Ann Surg 2020; 271: 1030-1035.

Authors: Patkova B, Svenningsson A, Almström M, Eaton S, Wester T, Svensson JF et al.

Scientific Surgery

Povidone-iodine irrigation for pediatric perforated appendicitis may be protective. A Bayesian pilot randomized controlled trial. Ann Surg 2020; 271: 827-833

Authors: Anderson KT, Putnam LR, Bartz-Kurycki MA, Hamilton EC, Yafi M, Pedroza C et al.

Scientific Surgery

Antibiotic treatment and appendectomy for uncomplicated acute appendicitis in adults and children. A systematic review and meta-analysis. Ann Surg 2019; 270: 1028-1040

Authors: Podda M, Gerardi C, Cillara N, Fearnhead N, Gomes CA, Birindelli A et al.

Scientific Surgery

Risk of appendiceal neoplasm in periappendicular abscess in patients treated with interval appendectomy vs follow-up with magnetic resonance imaging. 1-year outcomes of the Peri–appendicitis Acuta randomized clinical trial. JAMA Surg 2019; 154: 200-207.

Authors: Mällinen J, Rautio T, Grönroos J, Rantanen T, Nordström P, Savolainen H et al.

Scientific Surgery

A randomized double blinded study to determine the effectiveness of utilizing intraperitoneal bupivacaine: does it reduce postoperative opioid use following laparoscopic appendectomy? Am J Surg 2019; 217: 479-482.

Authors: Sevensma K, Schleichert T, Shwickerath C, Shoemaker A, Miller C

Scientific Surgery

Five-year follow-up of antibiotic therapy for uncomplicated acute appendicitis in the APPAC randomized clinical trial. JAMA 2018; 320: 1259-1265.

Authors: Salminen P, Hannu Paajanen T, Rautio T, Nordström P, Aarnio M, Rantanen T et al.

Scientific Surgery

Comparison of superficial surgical site infection between delayed primary versus primary wound closure in complicated appendicitis: a randomized controlled trial. Ann Surg 2018; 267: 631-637.

Authors: Siribumrungwong B, Chantip A, Noorit P, Wilasrusmee C, Ungpinitpong W, Chotiya P et al.

Scientific Surgery

Optimal stump management in laparoscopic appendectomy: a network meta-analysis by the Minimally Invasive Surgery Synthesis of Interventions and Outcomes Network. Surgery 2017: 162: 994-1005.

Authors: Antoniou SA, Mavridis D, Hajibandeh S, Antoniou GA, Gorter R, Tenhagen M et al.

Scientific Surgery

Antibiotics versus surgical therapy for uncomplicated appendicitis: systematic review and meta-analysis of controlled trials (PROSPERO 2015: CRD42015016882). Ann Surg 2017; 265: 889-900.

Authors: Harnoss J, Zelienka I, Probst P, Grummich K, Müller-Lantzsch C, Harnoss J et al.

Scientific Surgery

Appendectomy skin closure technique, randomized controlled trial: changing paradigms (ASC). World J Surg 2016; 40: 2603–2610.

Authors: Andrade LAM, Munoz FYP, Baez MVJ, Collazos SS, Ferretiz MAM, Ruiz B et al.

Scientific Surgery

Antibiotics versus appendicectomy for the treatment of uncomplicated acute appendicitis: an updated meta-analysis of randomised controlled trials. World J Surg 2016; 40: 2305–2318.

Authors: Rollins K, Varadhan KK, Neal KR, Lobo DN