The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Radioactive seed localization or wire-guided localization of nonpalpable invasive and in situ breast cancer: a randomized, multicenter, open-label trial. Ann Surg 2017; 266: 29-35.

Published: 30th September 2017

Authors: Langhans L, Tvedskov T, Klausen T, Jensen M-J, Talman M-L, Vejborg I et al.

Conclusion

Radioactive seed localization may be more convenient, as it can be done several days before surgery, and it did not increase the risk of positive resection margins (11.8 versus 13.3 per cent, P=0.65) in this study that included 409 patients.

Pubmed Link