This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Radiofrequency ablation vs. endoscopic surveillance for patients with Barrett esophagus and low-grade dysplasia. A randomized clinical trial. JAMA 2014; 311: 1209-1217.

Published: 13th November 2014

Authors: Phao KN, van Vilsteren FGI, Weusten BLAM, Bisschops R, Schoon EJ, Ragunath K et al. et al.

Conclusion

A total of 136 patients were followed for three years. The trial was stopped early because ablation reduced the rate of progression to high grade dysplasia from 26.5 to 1.5 per cent (P<0.001) and the risk of progression to adenocarcinoma from 8.8 to 1.5 per cent (P=0.03).

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