The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Randomised controlled trial of mesalazine in IBS. Gut 2016; 65: 82-90.

Published: 13th July 2016

Authors: Giovanni B, Cremon C, Annese V, Basilisco G, Bazzoli M, et al. et al.

Conclusion

Some 185 patients with IBS (irritable bowel syndrome) were treated for 12 weeks. Response rates were similar with mesalazine (68.6 per cent) and placebo (67.4 per cent). A small subgroup of patients did report sustained improvement.

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