This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Randomized controlled trial of botulinum toxin versus laparoscopic Heller myotomy for esophageal achalasia. Ann Surg 2004; 239: 364-370.

Published: 1st January 2004

Authors: Zananitto G, Annese V, Costantini M, Del Genio A, Costantino M, Epifani M et al. et al.

Conclusion

Eighty patients were included. After six months the effects of the two treatments on lower oesophageal sphincter pressure were similar, though symptom scores improved more in the surgical patients. Later on, symptoms recurred in 65 per cent of the patients given botulinum toxin.

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