This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A randomized controlled trial of vagus nerve-preserving distal gastrectomy versus conventional distal gastrectomy for postoperative quality of life in early stage gastric cancer patients. Ann Surg 2016; 263: 1079-1084.

Published: 18th August 2016

Authors: Kim S, Cho J, Kang D, Oh SJ, Kim AR, Sohn TS et al.

Conclusion

In this study that included 163 procedures, vagus preserving distal gastrectomy resulted in less diarrhoea after three months (P= 0.04) and 12 months (P=0.048). Appetite was improved and weight loss reduced. Cancer recurrence rates at five years were not significantly different.

You may also be interested in

Scientific Surgery

Effect of a deep learning-based system on the miss rate of gastric neoplasms during upper gastrointestinal endoscopy: a single-centre, tandem, randomised controlled trial. Lancet Gastro Hepatol 2021; 6: 700-708.

Authors: Wu L, Shang R, Sharma P, Zhou W, Liu J, Yao L et al.

Scientific Surgery

Short-term outcomes of robotic gastrectomy vs laparoscopic gastrectomy for patients with gastric cancer. A randomized clinical trial. JAMA Surg 2021; 156: 954-963.

Authors: Ojima T, Nakamura M, Hayata K, Kitadani J, Katsuda M, Takeuchi A et al.

Scientific Surgery

Assessment of robotic versus laparoscopic distal gastrectomy for gastric cancer. A randomized controlled trial. Ann Surg 2021; 273: 858-867.

Authors: Lu J, Zheng C-H, Xu B-B, Xie J-W, Wang J-B, Lin J-X et al.

Scientific Surgery

Effect of laparoscopic distal gastrectomy vs open distal gastrectomy on long-term survival among patients with stage I gastric cancer. The KLASS-01 Randomized Clinical Trial. JAMA Oncol 2019; 5: 506-513.

Authors: Kim H-H, Han S-U, Kim M-C, Kim W, Le H-J, Ryu SW et al.

Scientific Surgery

Pouch versus no pouch following total gastrectomy: meta-analysis of randomized and non-randomized studies. Ann Surg 2019; 269: 1041-1053.

Authors: Syn N, Wee I, Shabbir A, Kim G, So JB-Y

Scientific Surgery

Effect of laparoscopic vs open distal gastrectomy on 3-year disease-free survival in patients with locally advanced gastric cancer. The CLASS-01 randomized clinical trial. JAMA 2019; 321: 1983-1992.

Authors: Yu J, Huang C, Sun Y, Su X, Cao H, Hu J et al.

Scientific Surgery

Comparison of 3D laparoscopic gastrectomy with a 2D procedure for gastric cancer: a phase 3 randomized controlled trial. Surgery 2018; 163: 300-304.

Authors: Zheng C-H, Lu J, Zheng H-L, Li P, Xie J-W, Wang J-B et al.

Scientific Surgery

Laparoscopy-assisted versus open D2 distal gastrectomy for advanced gastric cancer: results from a randomized phase II multicenter clinical trial (COACT 1001). Ann Surg 2018; 267: 638-645.

Authors: Park YK, Yoon HM, Kim Y-W, Park JY, Ryu KW, Lee Y-J et al.

Scientific Surgery

Roux-en-Y or Billroth II reconstruction after radical distal gastrectomy for gastric cancer: a multicenter randomized controlled trial. Ann Surg 2018; 267: 236-242.

Authors: So JB-Y, Rao J, Wong AS-Y, Chan Y-H, Pang NQ, Tay AYL et al.

Scientific Surgery

Effect of intravenous ferric carboxymaltose on hemoglobin response among patients with acute isovolemic anemia following gastrectomy. The FAIRY Randomized Clinical Trial. JAMA. 2017; 317: 2097-2104.

Authors: Kim Y-W, Bae J-M, Park Y-K, Yang H-K, Yu W, Yook JH et al.

Scientific Surgery

Randomized controlled trial to evaluate splenectomy in total gastrectomy for proximal gastric carcinoma. Ann Surg 2017; 265: 277-283.

Authors: Sano T, Sasako M, Mizusawa J, Yamamoto S, Katai H, Yoshikawa T et al.

Scientific Surgery

A randomized phase II study of the clinical effects of ultrasonically activated coagulating shears (Harmonic scalpel) in open gastrectomy for gastric cancer. Surg Today 2016; 46: 561–568.

Authors: Kawabata R, Takiguchi S, Kimura Y, Imamura H, Fujita J, Tamura S et al.