This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Randomized, double-blind, controlled trial of early endoscopic ultrasound-guided celiac plexus neurolysis to prevent pain progression in patients with newly diagnosed, painful, inoperable pancreatic cancer. J Clin Oncol 2011; 29: 3541–3546.
Published: 21st February 2012
Authors: Wyse JM, Carone M, Paquin SC, Usatill M, Sahai AV
Conclusion
Ninety-six patients were included. There was no effect on quality of life or survival. Coeliac plexus block significantly reduced pain scores after one (P=0.09) and three months (P=0.01), and tended to reduce the need for morphine consumption at three months.
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