This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Randomized phase II study evaluating palbociclib in addition to letrozole as neoadjuvant therapy in estrogen receptor–positive early breast cancer: PALLET trial. J Clin Oncol 2019; 37: 178-189.
Published: 12th November 2019
Authors: Johnston S, Puhalla S, Wheatley D, Ring A, Barry P, Holcombe C et al.
Conclusion
Adding palbociclib to letrozole did not improve the rate of complete/partial response (54.3 versus 49.5 per cent, respectively) in this study that included 307 women.
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