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Randomized phase II study evaluating palbociclib in addition to letrozole as neoadjuvant therapy in estrogen receptor–positive early breast cancer: PALLET trial. J Clin Oncol 2019; 37: 178-189.

Published: 12th November 2019

Authors: Johnston S, Puhalla S, Wheatley D, Ring A, Barry P, Holcombe C et al.


Adding palbociclib to letrozole did not improve the rate of complete/partial response (54.3 versus 49.5 per cent, respectively) in this study that included 307 women.

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