This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Recovery after open versus laparoscopic pyloromyotomy for pyloric stenosis: a double blind multicentre randomised trial Lancet 2009; 373: 390-398

Published: 1st January 2009

Authors: Hall NJ, Pacilli M, Eaton S, Reblock K, Gaines BA, Pastor A et al et al.

Conclusion

Perioperative complication rates were similar after each procedure in this trial that included 180 infants. Laparoscopic pyloromyotomy was associated with faster return to full feeding (18.5 vs. 23.9h, P=0.002) and shorter hospital stay (33.6 vs. 43.8h, P=0.027

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IMPPACT (Intravenous Monotherapy for Postoperative Perforated Appendicitis in Children Trial). Randomized clinical trial of monotherapy versus multi-drug antibiotic therapy. Ann Surg 2021; 274: 406-410.

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A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis. Results of the COMMA Trial. Ann Surg 2021; 274: 240-247.

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Assessment of robotic versus laparoscopic distal gastrectomy for gastric cancer. A randomized controlled trial. Ann Surg 2021; 273: 858-867.

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