This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Saline versus Plasma-lyte in initial resuscitation of trauma patients: a randomized trial. Ann Surg 2014; 259: 255-262.

Published: 11th September 2014

Authors: Young JB, Utter GH, Schermer CR, Galante J, Phan HH, Yang Y et al. et al.

Conclusion

Forty-six severely injured patients with systolic blood pressure <90mmHg on admission were included. Up to 24h, resuscitation with Plasma-lyte improved base excess (mean difference 3.1 (95 per cent confidence interval 0.5 to 5.6), and reduced serum chloride.

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