The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Selective digestive or oropharyngeal decontamination and topical oropharyngeal chlorhexidine for prevention of death in general intensive care: systematic review and network meta-analysis. BMJ 2014; 348: g2197.

Published: 11th June 2014

Authors: Price R, MacLennan G, Glen J, on behalf of the SuDDICU collaboration

Conclusion

Twenty-nine studies were included. Selective digestive and oropharyngeal decontamination using poorly absorbed antibiotics was superior to oropharyngeal chlorhexidine at reducing mortality in intensive care. 

Pubmed Link