The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Surgery versus conservative treatment for recurrent and ongoing left-sided diverticulitis (DIRECT Trial): an open-label, multicentre, randomised controlled trial. Lancet Gastroenterol Hepatol 2017; 2: 13-22.

Published: 2nd February 2017

Authors: Van de Wall BJM, Stam MAW, Draaisma WA, Stellato R, Bemelman WA, Boermeester MA et al.

Conclusion

The trial was stopped early after 109 patients because of difficulties in recruitment. Some 15 per cent of surgical patients had an anastomotic leak; 23 per cent of conservatively treated patients eventually had surgery. Overall major complications were similar between the groups. At six months, quality of life was better after surgery (P<0.0001).

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Operative strategies for perforated diverticulitis. A systematic review and meta-analysis. Dis Colon Rectum 2018; 61: 1442-1453.

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