The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Surgical versus conservative management for subclinical Cushing syndrome in adrenal incidentalomas: a prospective randomized study Ann Surg 2009; 249: 388-91

Published: 1st January 2009

Authors: Toniato A, Merante-Boschin I, Opocher G, Pelizzo MR, Schiavi F, Ballotta E et al.

Conclusion

A total of 45 patients were randomized to laparoscopic adrenalectomy or observation over a 15-year interval. After mean follow-up of 7.7 years, three patients in the conservative group needed surgery for an enlarging adrenal mass. Conservative patients tended to get worsening diabetes and hypertension, whereas symptoms in surgical patients tended to improve

Pubmed Link