This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Synthetic versus biological mesh in laparoscopic and open ventral hernia repair (LAPSIS). Results of a multinational, randomized, controlled, and double-blind trial. Ann Surg 2021; 273: 57-65.

Published: 7th April 2021

Authors: Miserez M, Lefering R, Famiglietti F, Mathes T, Seidel D, Sauerland S et al.

Conclusion

This study that included 253 procedures was terminated early after interim analysis revealed higher major complication rates (including recurrence) with Surgisis Gold biological mesh than standard prosthetic mesh in both open (22.7 versus 9.8 per cent) and laparoscopic repairs (27.4 versus 10.9 per cent); P=0.013 overall.

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Meta-analysis and systematic review of the use of a prosthetic mesh for prevention of parastomal hernia. Ann Surg 2021; 274: 20-28.

Authors: Prudhomme M, Fabbro-Peray P, Rullier E, Occean BV, Bertrand MM

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Robotic versus laparoscopic ventral hernia repair. One-year results from a prospective, multicenter, blinded randomized controlled trial. Ann Surg 2021; 273: 1076-1080.

Authors: Dhanani N, Olavarria O, Holihan J, Shah S, Wilson T, Loor M et al.

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Prophylactic single-use negative pressure dressing in closed surgical wounds after incisional hernia repair. A randomized, controlled trial. Ann Surg 2021; 273: 1081-1086.

Authors: Bueno-Lledó J, Franco-Bernal A, Garcia-Voz-Mediano MT, Torregrosa-Gallud A, Bonafé S

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Preventing recurrence in clean and contaminated hernias using biologic versus synthetic mesh in ventral hernia repair. The PRICE randomized clinical trial. Ann Surg 2021; 273: 648-655.

Authors: Harris H, Primus F, Young C, Carter JT, Lin M, Mukhtar R et al.

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Patient-reported outcomes of robotic vs laparoscopic ventral hernia repair with intraperitoneal mesh. The PROVE-IT randomized clinical trial. JAMA Surg 2021; 156: 22-29.

Authors: Petro CC, Zolin S, Krpata D, Alkhatib H, Tu C, Rosen MJ et al.

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Five year follow-up of a randomized controlled trial of laparoscopic repair of very large hiatus hernia with sutures versus absorbable versus nonabsorbable mesh. Ann Surg 2020; 272: 241-247.

Authors: Watson DI, Thompson SK, Devitt PG, Aly A, Irvine T, Woods SD et al.

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Prevention of fascial dehiscence with onlay prophylactic mesh in emergency laparotomy: a randomized clinical trial. J Am Coll Surg 2020; 230: 76-87.

Authors: Lima HVG, Rassian R, Novo FCF, Bernini CO, Montero EFS, Utiyama EM et al.

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Primary fascial closure during laparoscopic ventral hernia repair improves patient quality of life. A multicenter, blinded randomized controlled trial. Ann Surg 2020; 271: 434-439

Authors: Bernardi K, Olavarria OA, Holihan JL, Kao LS, Ko TC, Roth JS et al.

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Prophylactic biological mesh Reinforcement versus Standard Closure of Stoma Site (ROCSS): a multicenter, randomized controlled trial. Lancet 2020; 395: 417-426

Authors: Reinforcement of Stoma Closure Site (ROCSS) Collaborative , West Midlands Research Collaborative

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Prophylactic intraperitoneal onlay mesh following midline laparotomy—long-term results of a randomized controlled trial. World J Surg 2019; 43: 1669-1675.

Authors: Glauser PM, Brosi P, Speich B, Kaser SA, Heigl A, Rosenberg R et al.

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Effectiveness of prophylactic intraperitoneal mesh implantation for prevention of incisional hernia in patients undergoing open abdominal surgery: a randomized clinical trial. JAMA Surg 2019; 154: 109-115.

Authors: Kohler A, Lavanchy JL, Lenoir U, Kurmann A, Candinas D, Beldi G et al.

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Prophylactic intraperitoneal onlay mesh reinforcement reduces the risk of incisional hernia, two-year results of a randomized clinical trial. World J Surg 2018; 42: 1687–1694.

Authors: Brosi P, Glauser PM, Speich B, Käser SA, Maurer CA