This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Tacrolimus versus microemulsified ciclosporin in liver transplantation: the TMC randomised controlled trial. Lancet 2002; 360: 1119-25

Published: 1st January 2002

Authors: O'Grady JG, Burroughs A, Hardy P, Elbourne D, Truesdale A and the UK and Republic of Ireland Liver Transplant Study Group

Conclusion

Some 606 transplants were studied; use of tacrolimus improved the outcome one year after transplantation by reducing the risk of death, retransplantation or treatment failure due to immunological reasons

Pubmed Link

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