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The effects of ganglioside-monosialic acid in taxane-induced peripheral neurotoxicity in patients with breast cancer: a randomized trial. J Natl Cancer Inst 2020; 112: 55–62

Published: 15th June 2020

Authors: Su Y, Huang J, Wang S, Unger JM, Arias-Fuenzalida J, Shi Y et al.


Some 206 women with early breast cancer due to receive adjuvant taxane chemotherapy were randomly allocated ganglioside-monosialic acid (GM1). After one year, women who had GM1 had lower neurotoxicity scores (P<0.001) and les peripheral neuropathy (26.4 versus 97.8 per cent, P<0.001).

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