The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

The prophylactic effect of aprotinin on intra-operative bleeding in liver transplantation: a randomized clinical study. Hepatology 1997; 26: 1143-8.

Published: 1st January 1997

Authors: Garcia-Huete L, Domenech P, Sabate A, Martinez-Brotons F, Jaurrieta E, Figueras J. et al.

Conclusion

There was no advantage in giving aprotinin during operation in this study of 80 patients. Intra-operative transfusion requirements were similar as were bleeding complications and mortality rates

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