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Ticagrelor and aspirin or aspirin alone in acute ischemic stroke or TIA. N Engl J Med 2020; 383: 207-217.

Published: 16th September 2020

Authors: Claiborne Johnston S, Amarenco P, Denison H, Evans SR, Himmelmann A, James S et al.


A total of 11,016 patients were randomized. The risk of death or stroke within 30 days was lower in the ticagrelor with aspirin group (5.5% versus 6.6 per cent for aspirin alone, P=0.02). The rate of disability at 30 days was similar in the two groups.

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