This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Ticagrelor and aspirin or aspirin alone in acute ischemic stroke or TIA. N Engl J Med 2020; 383: 207-217.

Published: 16th September 2020

Authors: Claiborne Johnston S, Amarenco P, Denison H, Evans SR, Himmelmann A, James S et al.

Conclusion

A total of 11,016 patients were randomized. The risk of death or stroke within 30 days was lower in the ticagrelor with aspirin group (5.5% versus 6.6 per cent for aspirin alone, P=0.02). The rate of disability at 30 days was similar in the two groups.

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