Upper GI - British Journal of Surgery

Scientific Surgery

Long-term efficacy of neoadjuvant chemoradiotherapy plus surgery for the treatment of locally advanced esophageal squamous cell carcinoma. The NEOCRTEC5010 randomized clinical trial. JAMA Surg 2021; 156: 721-729.

Authors: Yang H, Liu H, Chen Y, Zhu C, Fang W, Yu Z et al.

Scientific Surgery

Intrathoracic vs cervical anastomosis after totally or hybrid minimally invasive esophagectomy for esophageal cancer. A randomized clinical trial. JAMA Surg 2021; 156: 601-610.

Authors: Van Workum F, Verstegen MHP, Klarenbeek BR, Bouwense SAW, van Berge Henegouwen MI, Daams F et al.

Scientific Surgery

Morbidity and mortality of patients who underwent minimally invasive esophagectomy after neoadjuvant chemo-radiotherapy vs neoadjuvant chemotherapy for locally advanced esophageal squamous cell carcinoma. A randomized clinical trial. JAMA Surg 2021; 156: 444-451.

Authors: Wang H, Tang H, Fang Y, Tan L, Yin J, Shen Y et al.

Scientific Surgery

Five-year survival outcomes of hybrid minimally invasive esophagectomy in esophageal cancer. Results of the MIRO Randomized Clinical Trial. JAMA Surg 2021; 156: 323-332.

Authors: Nuytens F, Dabakuyo-Yonli TS, Meunier B, Gagnière J, Collet D, D’Journo XB et al.

Scientific Surgery

Palliative radiotherapy after oesophageal cancer stenting (ROCS): a multicentre, open-label, phase 3 randomised controlled trial. Lancet Gastroenterol Hepatol 2021; 6: 292-303.

Authors: Adamson DA, Byrne A, Porter C, Blazeby J, Griffiths G, Nelson A et al.

Scientific Surgery

Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer (EXPEL): a multicentre randomised controlled trial. Lancet Gastro Hepatol 2021; 6: 120-127.

Authors: Kono K, Misawa K, Yabusaki H, Kinoshita T, Lau PC, Kim YW et al.

Scientific Surgery

Assessment of robotic versus laparoscopic distal gastrectomy for gastric cancer. A randomized controlled trial. Ann Surg 2021; 273: 858-867.

Authors: Lu J, Zheng C-H, Xu B-B, Xie J-W, Wang J-B, Lin J-X et al.

Scientific Surgery

Adjuvant nivolumab in resected esophageal or gastroesophageal junction cancer. N Engl J Med 2021; 384: 1191-1203.

Authors: Kelly RJ, Ajani JA, Kuzdzal J, Zander T, van Cutsem E, Piessen G et al.

Scientific Surgery

Safety and efficacy of indocyanine green tracer-guided lymph node dissection during laparoscopic radical gastrectomy in patients with gastric cancer. A randomized clinical trial. JAMA Surg 2020; 155: 300-311.

Authors: Chen Q-Y, Xie J-W, Zhong Q, Wang J-B, Lin J-X, Lu J et al.

Scientific Surgery

Surgical morbidity and mortality from the multicenter randomized controlled NeoRes II Trial. Standard versus prolonged time to surgery after neoadjuvant chemoradiotherapy for esophageal cancer. Ann Surg 2020; 272: 684-689.

Authors: Nilsson K, Klevebro F, Rouvelas I, Lindblad M, Szabo E, Halldestam I et al.

Scientific Surgery

Health-related quality of life following hybrid minimally invasive versus open esophagectomy for patients with esophageal cancer. Analysis of a multicenter, open-label, randomized phase III controlled trial. The MIRO Trial. Ann Surg 2020; 271: 1023-1029.

Authors: Mariette C, Markar S, Dabakuyo-Yonli TS, Meunier B, Pezet D, Collet D et al.

Scientific Surgery

Effect of laparoscopic distal gastrectomy vs open distal gastrectomy on long-term survival among patients with stage I gastric cancer. The KLASS-01 Randomized Clinical Trial. JAMA Oncol 2019; 5: 506-513.

Authors: Kim H-H, Han S-U, Kim M-C, Kim W, Le H-J, Ryu SW et al.

Scientific Surgery

Survival outcomes after laparoscopy-assisted distal gastrectomy versus open gastrectomy with nodal dissection for clinical stage 1A or 1B gastric cancer (JCOG0912): a multicenter, non-inferiority, phase 3 randomised controlled trial. Lancet Gastroenterol Hepatol 2020; 5: 142-151

Authors: Katai H, Mizusawa J, Katayama H, Morita S, Yamada T, Brando E et al.

Scientific Surgery

Short-term outcomes of a multicenter randomized controlled trial comparing laparoscopic distal gastrectomy with D2 lymphadenectomy to open distal gastrectomy for locally advanced gastric cancer (KLASS-02-RCT). Ann Surg 20129; 270: 983-991

Authors: Lee H-J, Hyung WJ, Yang H-K, Han S, Park Y-K, An JY et al.

Scientific Surgery

Combined surgery and extensive intraoperative peritoneal lavage vs surgery alone for treatment of locally advanced gastric cancer. The SEIPLUS randomized clinical trial. JAMA Surg 2019; 154: 610-616

Authors: Guo J, Xu A, Sun X, Zhao X, Xia Y, Rao H et al.

Scientific Surgery

Effect of laparoscopic vs open distal gastrectomy on 3-year disease-free survival in patients with locally advanced gastric cancer. The CLASS-01 randomized clinical trial. JAMA 2019; 321: 1983-1992.

Authors: Yu J, Huang C, Sun Y, Su X, Cao H, Hu J et al.

Scientific Surgery

Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial. Lancet 2019; 393: 1948-1957.

Authors: Al-Batran S-E, Homann N, Pauligk C, Goetze TO, Meiler J, Kasper S et al.

Scientific Surgery

Robot-assisted minimally invasive thoracolaparoscopic esophagectomy versus open transthoracic esophagectomy for resectable esophageal cancer. A randomized controlled trial. Ann Surg 2019; 269: 621-630.

Authors: van der Sluis PC, van der Horst S, May AM, Schippers C, Brosens L, Joore HC et al.

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