This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A randomized, double‐blind, placebo‐controlled trial of probiotics to reduce the severity of oral mucositis induced by chemoradiotherapy for patients with nasopharyngeal carcinoma. Cancer 2019; 125: 1081-1090

Published: 5th March 2020

Authors: Jiang C, Wang H, Xia C, Dong Q, Chen E, Qiu Y et al.

Conclusion

Some 99 patients were randomized 2:1. The rate of severe oral mucositis was reduced from 45.7 to 15.5 per cent, P<0.05. The probiotics significantly enhanced measures of immune system function, and maintained intestinal microbial diversity.

Pubmed Link

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