Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Chemoembolization combined with radiofrequency ablation for patients with hepatocellular carcinoma larger than 3cm. JAMA 2008; 299: 1669-1677.

Authors: Cheng B-Q, Jia C-Q, Liu C-T, Fan W, Wang Q-L, Zhang Z-L et al. et al.

Scientific Surgery

Methylprednisolone therapy in deceased donors reduces inflammation in the donor liver and improves outcome after liver transplantation: a prospective randomised controlled trial Ann Surg 2008; 248: 1042¿50

Authors: Kotsch K, Ulrich F, Reutzel-Selke A, Pascher A, Faber WW, Hoffman S et al et al.

Scientific Surgery

A prospective randomized trial of acute normovolemic hemodilution compared to standard intraoperative management in patients undergoing major hepatic resection Ann Surg 2008; 248: 360-369

Authors: Jarnagin WR, Gonen M, Maithel SK, Fong Y, D¿Angelica MI, DeMatteo RP et al et al.

Scientific Surgery

Intraoperative blood salvage during liver resection: a randomized controlled trial. Ann Surg 2007; 245: 686-691.

Authors: Hashimoto T, Kodudo N, Orii R, Seyama Y, Sano K, Imamura H et al.

Scientific Surgery

Chemoprevention of primary liver cancer: a double blind trial in Linxian, China. J Natl Cancer Inst 2007; 99: 1240-1247.

Authors: Qu C-X, Kamangar F, Fan J-H, Yu B, Sun X-D, Taylor PR et al.

Scientific Surgery

Randomized clinical trial of radiofrequency-assisted versus clamp-crushing liver resection. Br J Surg 2007; 94: 287-291.

Authors: Lupo L, Gallerani A, Panzera P, Tandoi F, Di Palma G, Memeo V. et al.

Scientific Surgery

Randomized clinical trial evaluating the need for routine nasogastric decompression after elective hepatic resection. Br J Surg 2007; 94: 297-303.

Authors: Pessaux P, Regimbeau JM, Dondéro F, Plasse M, Mantz J, Belghiti J. et al.

Scientific Surgery

Partial hepatectomy with wide versus narrow resection margin for solitary hepatocellular carcinoma: a prospective randomized trial. Ann Surg 2007; 245: 36-43.

Authors: Shi M, Guo R-P, Lin X-J, Zhang Y-Q, Chen M-S, Zhang C-Q et al.

Scientific Surgery

Application of fibrin glue sealant after hepatectomy does not seem justified: results of a randomized study in 300 patients. Ann Surg 2007; 245: 536-542.

Authors: Figueras J, Llado L, Miro M, Ramos E, Torras J, Fabregat J et al.

Scientific Surgery

A prospective, randomized, controlled trial comparing intermittent portal triad clamping versus ischemic preconditioning with continuous clamping for major liver resection. Ann Surg 2006; 244: 921¿930.

Authors: Petrowsky H, McCormack L, Trujillo M, Selzner M, Jochum W, Clavien P-A. et al.

Scientific Surgery

Multicenter randomized trial of adjuvant fluorouracil and folinic acid compared with surgery alone after resection of colorectal liver metastases: FFCD ACHBTH AURC 9002 Trial. J Clin Oncol 2006; 24: 4976¿4982.

Authors: Portier G, Elias D, Bouche O, Rougier P, Bosset J-F, Saric J et al.

Scientific Surgery

Ischemic preconditioning versus intermittent vascular occlusion in liver resections performed under selective vascular exclusion: a prospective randomized study. Am J Surg 2006; 192: 669¿674.

Authors: Smyrniotis V, Theodoraki K, Arkadopoulos N, Fragulidis G, Condi-Pafiti A, Plemenou-Fragou M et al.

Scientific Surgery

Efficacy of postoperative transarterial chemoembolisation and portal vein chemotherapy for patients with hepatocellular carcinoma complicated by portal vein tumor thrombosis ¿ a randomized study. World J Surg 2006; 30: 2004¿2011.

Authors: Li Q, Wang J, Sun Y, Cui YL, Juzi JT, Li HX et al.

Scientific Surgery

A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma. Ann Surg 2006; 243: 321¿328.

Authors: Chen M-S, Li J-Q, Zheng Y, Guo R-P, Liang H-H, Zhang Y-Q et al.

Scientific Surgery

Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481) J Clin Oncol 2006; 24: 1395¿1403.

Authors: Kemeny NE, Niedzwiecki D, Hollis DR, Lenz H-J, Warren RS, Naughton MJ et al.

Scientific Surgery

Chemoocclusion vs. chemoperfusion for treatment of advanced hepatocellular carcinoma: a randomized trial. Eur J Surg Oncol 2006; 32: 201¿7.

Authors: Kirchhoff TD, Rudolph KL, Layer G, Chavan A, Greten TF, Rosenthal H et al.

Scientific Surgery

Randomized clinical trial of the effects of abdominal drainage after elective hepatectomy using the crushing clamp method. Br J Surg 2006; 93: 422¿426.

Authors: Sun H.-C, Quin L.-X, Lu L, Wang L, Ye Q.-H, Ren N et al.

Scientific Surgery

Randomized clinical trial of liver resection with and without hepatic pedicle clamping. Br J Surg 2006; 93: 685¿689.

Authors: Capussotti L, Muratore A, Ferrero A, Massucco P, Ribero D, Polastri R. et al.

Scientific Surgery

Randomized clinical trial of hepatectomy using intermittent pedicle occlusion with ischaemic intervals of 15 versus 30 minutes. Br J Surg 2006; 93: 944¿951.

Authors: Esaki M, Sano T, Shimada K, Sakamoto Y, Takahashi Y, Wakai K et al.

Scientific Surgery

Usefulness of LigaSure for liver resection: analysis of randomized clinical Am J Surg 2006; 192: 41?45.

Authors: Saiura A, Yamamoto J, Koga R, Sakamoto Y, Kokudo N, Seki M et al.

Scientific Surgery

Randomized clinical trial of the effect of a saline-linked radiofrequency coagulator on blood loss during hepatic resection. Br J Surg 2005; 92: 954¿959.

Authors: Arita J, Hasegawa K, Kokudo N, Sano K, Sugawara Y, Makuuchi M. et al.

Scientific Surgery

Sharp liver transection versus clamp crushing technique in liver resections: a prospective study. Surgery 2005; 137: 306-311.

Authors: Smyrniotis V, Arkadopoulos N, Kostopanagiotou G, Farantos C, Vassiliou J, Contis J et al.

Scientific Surgery

Complete versus selective portal triad clamping for minor liver resections: a prospective randomized trial. Ann Surg 2005; 241: 582-590.

Authors: Figueras J, Llado L, Ruiz D, Ramos E, Busquets J, Rafecas A et al.

Scientific Surgery

Randomized clinical trial of the effect of intravenous fluid administration in patients with obstructive jaundice undergoing endoscopic drainage. Br J Surg 2005; 92: 39¿43.

Authors: Padillo FJ, Briceno J, Cruz A, Chicano M, Naranjo A, Vallejo J et al.

Scientific Surgery

Randomized controlled trial of tamoxifen in advanced hepatocellular carcinoma. J Clin Oncol 2005; 23: 4338ý4346.

Authors: Barbare JC, Bouche O, Bonnetain F, Raoul JL, Rougier P, Abergel A et al.

Scientific Surgery

Percutaneous ethanol injection versus surgical resection for the treatment of small hepatocellular carcinoma: A prospective study. Ann Surg 2005; 242: 36-42.

Authors: Huang G-T, Lee P-H, Tsang Y-M, Lai M-Y, Yang P-M, Hu R-H et al.

Scientific Surgery

Comparison of a new fibrin sealant with standard topical hemostatic agents. Arch Surg 2004; 139: 1148-1154.

Authors: Schwartz M, Madariaga J, Hirose R, Shaver TR, Sher L, Chari R et al. et al.

Scientific Surgery

Prospective randomized controlled study of interferon-alpha in preventing hepatocelluar carcinoma recurrence after medical ablation therapy for primary tumors. Cancer 2004; 100: 376-382.

Authors: Lin S-M, Lin C-J, Hsu C-W, Tai D-I, Sheen I-S, Lin D-Y et al. et al.

Scientific Surgery

Prevention of pleural effusion following hepatectomy using argon beam coagulation Br J Surg 2003; 90: 302-5.

Authors: Kwon A-H, Matsui Y, Satoi S, Kaibori M, Kamiyama Y.

Scientific Surgery

Selective hepatic vascular exclusion versus Pringle Maneuver in major liver resections: prospective study World J Surg 2003; 27: 765-769.

Authors: Smyrniotis VE, Kostopanagiotou GG, Contis JC, Farantos CI, Voros DC, Kannas DC et al et al.

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