This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of intravenous acetaminophen on postoperative hypoxemia after abdominal surgery. The FACTOR Randomized Clinical Trial. JAMA 2020; 324: 350-358.

Published: 16th September 2020

Authors: Turan A, Essber H, Saasouh W, Hovsepyan K, Makarova I, Ayad S et al.

Conclusion

In this study that included 580 patients, routine use of paracetamol for 48h did not reduce the length of time oxygen saturation was below 90%, pain scores or opioid requirement.

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Intravenous patient-controlled analgesia versus thoracic epidural analgesia after open liver surgery. A prospective, randomized, controlled, noninferiority trial. Ann Surg 2019; 270: 193-199

Authors: Hausken J, Fretland AA, Edwin B, Andersen MH, Dagenborg VJ, Bjørnelv GMW et al.

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A 96‐hour continuous wound infiltration with ropivacaine reduces analgesic consumption after liver resection: A randomized, double‐blind, controlled trial. J Surg Oncol 2019; 119: 47-55

Authors: Peres‐Bachelot V, Blanc E, Oussaid N, Perol D, Daunizeau-Walker AL, Pouderoux S et al.

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Preperitoneal or subcutaneous wound catheters as alternative for epidural analgesia in abdominal surgery. A systematic review and meta-analysis. Ann Surg 2019; 269: 252-260.

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