This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Two phase 3 trials of adalimumab for hidradenitis suppurativa. N Engl J Med 2016; 375: 422-434.

Published: 21st September 2016

Authors: Kimball AB, Okun MM, Williams DA, Gottlieb AB, Papp KA, Zouboulis CC et al.

Conclusion

Over 600 patients were treated in two studies. Clinical response rates after 12 weeks were significantly higher in both studies: 41.8 vs. 26 per cent; and 58.9 vs. 27.6 per cent. Serious adverse events were rare.

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