This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of perioperative gabapentin on postoperative pain resolution and opioid cessation in a mixed surgical cohort. A randomized clinical trial. JAMA Surg 2018; 153: 303-311.

Published: 9th August 2018

Authors: Ha J , Mackey SC, Schmidt P, McCue R, Humphreys K, Trafton J et al.

Conclusion

A total of 410 procedures were included. Gabapentin did not reduce the time to pain cessation (hazard ratio 1.04, 95 per cent confidence interval 0.82 to 1.33; P=0.73). It did cause a small reduction in opioid use.

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